Tirosint Efficacy

Consistent Dissolution Regardless of Gastric pH

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Clinical studies have demonstrated the role of gastric acidity in the absorption of levothyroxine. Patients with GI conditions, or those taking concomitant drugs that affect gastric acidity, may suffer from variable levels of gastric pH which may inhibit the absorption of traditional levothyroxine formulations. Tirosint’s® unique gel cap formulation is unaffected by gastric pH.³’⁴

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Consistent Absorption in the Presence of GI Disorders

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Certain gastro-intestinal (GI) disorders can impair the absorption of traditional levothyroxine formulations. Tirosint® has been shown to be effective among patients in who suffer from GI conditions.⁵

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Consistent Absorption Even When Taken With Black Coffee

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Dietary intake has been shown to affect the absorption of traditional levothyroxine formulations. Tirosint® has been shown to be unaffected by the intake of black coffee.⁶

  • TSH levels remained consistent in patients taking Tirosint regardless of when coffee was ingested (1 hour after dosing vs ≤ 5 minutes after dosing)
  • Impaired T4 absorption was noted with all T4 preparations when ingested with dairy

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